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What Is PONVORY®? | PONVORY® (ponesimod)

PONVORY® is used to treat relapsing multiple sclerosis (MS) in adults

PONVORY® was proven to help control the symptoms and signs of relapsing MS

In the ~2-year clinical study, PONVORY® was:


SUPERIOR at reducing the number of relapses per year vs a proven oral therapy (Aubagio®)


SUPERIOR at reducing the number of lesions vs a proven oral therapy (Aubagio®)*

3-month disability

SIMILAR at slowing 3-month disability progression vs a proven oral therapy (Aubagio®). There was no statistically significant difference in the percentages of people experiencing disability progression between PONVORY® and Aubagio®

*PONVORY® reduced the average number of new gadolinium-enhancing T1 and new or enlarging T2 lesions.

Your daily PONVORY® journey


PONVORY® is an oral, once-daily pill that can be taken anywhere. Most people can take their first dose at home


Unlike injections or infusions, no refrigeration, special storage, or trips to infusion centers are required


Can be taken with or without food and has no known food restrictions

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Has no known drug interactions with selective serotonin reuptake inhibitors (SSRIs), the most commonly prescribed class of antidepressants

First dose monitoring is required for people with certain cardiac conditions (slow heart rate, certain types of heart block, and heart attack or heart failure occurring >6 months prior to treatment initiation and in stable condition). Supervision of this first dose should take place in a healthcare setting.

Tip: To help you remember to take your pill each day, try combining the habit with something you already do every day, like brushing your teeth, putting on your pajamas, or even walking your dog.

How does PONVORY® work?

If you have MS, your body’s own immune cells attack your central nervous system (CNS).

The exact way PONVORY® works in MS is unknown, but it is believed to work by reducing the number of immune cells, called lymphocytes, in the blood. This may help keep lymphocytes out of the CNS where they could cause damage.